Mechanisms of Action
Through rigorous research and testing, Kyolic Aged Garlic Extract™ can be characterized as having the following mechanisms of action:
| EFFECT | MECHANISM |
|---|---|
| Inhibition of Plaque Formation in the Coronary Artery* | Improves vessel function through antioxidant properties and inhibits scavenger receptor expression, foam cell formation, and smooth muscle cell proliferation associated with plaque formation.* |
| Improvement of Endothelial Function in Macro- and Microcirculation* | Maintains blood pressure and blood flow through antioxidant properties (e.g. directly scavenges reactive oxygen species (ROS), modulates NF-kB signal pathway and glutathione redox cycle by enhancing antioxidant enzymes and intracellular antioxidant glutathione, enhances good nitric oxide (NO) production and reduces risk factors such as high cholesterol and homocysteine levels).* |
| HDL Enhancing* | Decreases LDL cholesterol while increasing HDL serum levels.* |
| Cholesterol Lowering* | Inhibits HMG-CoA reductase (an enzyme that forms cholesterol).* Inhibits absorption of cholesterol in the gastrointestinal tract.* |
| Inhibition of LDL-cholesterol Oxidation* | Antioxidant properties such as metal chelating, directly scavenging reactive oxygen species and inhibiting lipid peroxidation.* |
| Inhibition of Platelet Aggregation* | Competes with agonists, such as adenosine diphosphate (ADP), collagen, etc., which are inducers of platelet aggregation by suppressing calcium mobilization.* |
| Effect on Sickle Cells* | Antioxidant properties.*
Reduces Heinz bodies, which cause damage to red blood cell membranes.* |
| Prevention of the Common Cold* | Enhances the immune system such as natural killer cells, macrophages, phagocytes, T-cells, increases antibody production and lymphocyte functions.* |
| Recovery from a Cold with General Fatigue* | Enhances the immune system.*
Stimulates various metabolic systems including assorted enzymes.* |
| Effects on Various Unexplained Complaints* | Enhances the immune system.*
Stimulates various metabolic systems, including assorted enzymes.* Stimulates both macro- and microcirculation, especially in the extremities.* |